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ToxPi : Toxicological Prioritization Index



Click on the link below to download the latest version of the Graphical User Interface (GUI). The .zip file includes the software, example data files, all required libraries, and a full user manual. 

     toxpi.zip (2 January 2018)

Contact the authors for previous versions.


Current release of the ToxPi interface:

     Marvel SW, To KT, Grimm F, Wright FA, Rusyn I, Reif DM. ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models. BMC  Bioinformatics . 2018. 19(1):80. PMID: 29506467.

Original paper introducing the ToxPi methodological framework:

     Reif DM, Martin MT, Tan SW, Houck KA, Judson RS, Richard AM, Knudsen TB, Dix DJ, Kavlock RF. Endocrine profiling and prioritization of environmental chemicals using ToxCast data. Environmental Health Perspectives.  2010. 118(12):1714-20. PMID: 20826373. 

Funding for development of the ToxPi interface:

     EPA STAR #R835802 (PIs: Ivan Rusyn, David Threadgill, Fred Wright)